{"product_id":"ala-r-sap-90-caps","title":"ALA R+ SAP 90 caps","description":"\u003cp\u003eSCIENCE-BASED R+ ALPHA-LIPOIC ACID FOR OPTIMAL ANTIOXIDANT PROTECTION\u003c\/p\u003e\n\u003cp\u003eOne of the leading causes of cellular breakdown is free radical damage and antioxidants are crucial to help protect against these deleterious effects. Alpha-Lipoic acid (ALA) R+ is the only antioxidant that is both fat- and water-soluble.[\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22125537\/\" title=\"Golbidi, S. et al. “Diabetes and alpha lipoic Acid”. Front Pharmacol. (2011 Nov 17): 2:69.\"\u003e1\u003c\/a\u003e] This is important because ALA can access all parts of living cells, giving it the ability to trap free radicals and protect against oxidation.[\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22125537\/\" title=\"Golbidi, S. et al. “Diabetes and alpha lipoic Acid”. Front Pharmacol. (2011 Nov 17): 2:69.\"\u003e1\u003c\/a\u003e] Also, ALA R+ is one of the few substances that can cross the blood-brain barrier.[\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2597694\/\" title=\"Voloboueva, L.A., et al. “(R)-α-Lipoic acid protects retinal pigment epithelial cells from oxidative damage.” Investigative Ophthalmology \u0026amp; Visual Science. Vol. 46, No. 11 (2005): 4302–4310.\"\u003e2\u003c\/a\u003e]\u003c\/p\u003e\n\u003cp\u003eALA constitutes an equal proportion of the R-(natural) and S-(unnatural) enantiomers that are mirror images of each other, also called a ‘racemic’ mixture.[\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22125537\/\" title=\"Golbidi, S. et al. “Diabetes and alpha lipoic Acid”. Front Pharmacol. (2011 Nov 17): 2:69.\"\u003e1\u003c\/a\u003e, \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2597694\/\" title=\"Voloboueva, L.A., et al. “(R)-α-Lipoic acid protects retinal pigment epithelial cells from oxidative damage.” Investigative Ophthalmology \u0026amp; Visual Science. Vol. 46, No. 11 (2005): 4302–4310.\"\u003e2\u003c\/a\u003e] \u003cstrong\u003eALA R+ SAP\u003c\/strong\u003e provides the natural form consisting only of the R(+) isomer, which is much more bioavailable than the standard ALA.[\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2597694\/\" title=\"Voloboueva, L.A., et al. “(R)-α-Lipoic acid protects retinal pigment epithelial cells from oxidative damage.” Investigative Ophthalmology \u0026amp; Visual Science. Vol. 46, No. 11 (2005): 4302–4310.\"\u003e2\u003c\/a\u003e] R-ALA and its reduced counterpart, dihydrolipoic acid (DHLA), are a potent antioxidant pair. Studies show that ALA has the ability to regenerate vitamin C, coenzyme Q10, glutathione, and vitamin E.[\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12086686\/\" title=\"Jones, W., Li. X., Qu. Z.C., Perriott. L., Whitesell. R.R., May. J.M. “Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells”. Free Radic Biol Med. Vol. 93 (2002): 33(1):83.\"\u003e3\u003c\/a\u003e, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10049509\/\" title=\"Kozlov. A.V., Gille. L., Staniek. K., Nohl. H. “Dihydrolipoic acid maintains ubiquinone in the antioxidant active form by two-electron reduction of ubiquinone and one-electron reduction of ubisemiquinone”. Arch Biochem Biophys. Vol. 154 (1999): 363(1):148\"\u003e4\u003c\/a\u003e, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9448716\/\" title=\"May. J.M., Qu. Z.C., Mendiratta. S. “Protection and recycling of alpha-tocopherol in human erythrocytes by intracellular ascorbic acid”. Arch Biochem Biophys. Vol. 289 (1998): 349(2):281.\"\u003e5\u003c\/a\u003e] Unlike ascorbic acid, DHLA can be recycled from ALA, and therefore is not destroyed by quenching free radicals.[\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22125537\/\" title=\"Golbidi, S. et al. “Diabetes and alpha lipoic Acid”. Front Pharmacol. (2011 Nov 17): 2:69.\"\u003e1\u003c\/a\u003e, \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2597694\/\" title=\"Voloboueva, L.A., et al. “(R)-α-Lipoic acid protects retinal pigment epithelial cells from oxidative damage.” Investigative Ophthalmology \u0026amp; Visual Science. Vol. 46, No. 11 (2005): 4302–4310.\"\u003e2\u003c\/a\u003e]\u003c\/p\u003e\n\u003cp\u003eBased on one study, there is a suggestion that ALA may reduce the amount of biotin in the body and hence biotin is added to this formulation to potentially alleviate biotin deficiency.[\u003ca href=\"https:\/\/doi.org\/10.1093\/jn\/127.9.1776\" title=\"Zempleni., J., et al. “Lipoic Acid Reduces the Activities of Biotin-Dependent Carboxylases in Rat Liver”. The Journal of Nutrition, Vol. 127, Issue 9, (September 1997): 1776–1781\"\u003e6\u003c\/a\u003e]\u003c\/p\u003e\n\u003cp\u003eNFH \u003cstrong\u003eALA R+ SAP\u003c\/strong\u003e can\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHelp improve antioxidants status in the body for optimal health.[\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22125537\/\" title=\"Golbidi, S. et al. “Diabetes and alpha lipoic Acid”. Front Pharmacol. (2011 Nov 17): 2:69.\"\u003e1\u003c\/a\u003e, \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2597694\/\" title=\"Voloboueva, L.A., et al. “(R)-α-Lipoic acid protects retinal pigment epithelial cells from oxidative damage.” Investigative Ophthalmology \u0026amp; Visual Science. Vol. 46, No. 11 (2005): 4302–4310.\"\u003e2\u003c\/a\u003e]\u003c\/li\u003e\n\u003cli\u003eHelp regenerate vitamin C, coenzyme Q10, glutathione, and vitamin E [\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12086686\/\" title=\"Jones, W., Li. X., Qu. Z.C., Perriott. L., Whitesell. R.R., May. J.M. “Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells”. Free Radic Biol Med. Vol. 93 (2002): 33(1):83.\"\u003e3\u003c\/a\u003e, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10049509\/\" title=\"Kozlov. A.V., Gille. L., Staniek. K., Nohl. H. “Dihydrolipoic acid maintains ubiquinone in the antioxidant active form by two-electron reduction of ubiquinone and one-electron reduction of ubisemiquinone”. Arch Biochem Biophys. Vol. 154 (1999): 363(1):148\"\u003e4\u003c\/a\u003e, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9448716\/\" title=\"May. J.M., Qu. Z.C., Mendiratta. S. “Protection and recycling of alpha-tocopherol in human erythrocytes by intracellular ascorbic acid”. Arch Biochem Biophys. Vol. 289 (1998): 349(2):281.\"\u003e5\u003c\/a\u003e]\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cmeta charset=\"UTF-8\"\u003eAdults:\u003cspan\u003e Take 1 capsule three times daily or as directed by your health-care practitioner.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEach non-GMO vegetable capsule contains:\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem data-mce-fragment=\"1\"\u003eR-\u003c\/em\u003e\u003cspan data-mce-fragment=\"1\"\u003ealpha-Lipoic acid\u003c\/span\u003e [\u003cem\u003ealpha\u003c\/em\u003e-lipoic acid \u003cem\u003eR\u003c\/em\u003e(+)]\u003c\/td\u003e\n\u003ctd\u003e150 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiotin\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp\u003e50 mcg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003eNPN\u003cspan\u003e 80025697\u003c\/span\u003e\u003c\/p\u003e","brand":"NFH","offers":[{"title":"Default Title","offer_id":39613214359655,"sku":"80025697","price":89.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0022\/7039\/6474\/products\/1379-ALA-R-SAP-90-capsules.jpg?v=1643150268","url":"https:\/\/shop.rediscoverhealth.ca\/en-ru\/products\/ala-r-sap-90-caps","provider":"Rediscover Health Online Dispensary ","version":"1.0","type":"link"}