{"product_id":"s-acetyl-glutathione-60-caps","title":"S-Acetyl Glutathione 60 caps","description":"\u003cul class=\"pi-list-with-icons pi-list-icons-right-open\" data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003eProvides antioxidants that help reduce the oxidative damage caused by free radicals\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eReduced glutathione, commonly known as glutathione or GSH, is\u003cbr\u003ea tripeptide consisting of L-glutamine, L-cysteine, and glycine. It\u003cbr\u003eis ubiquitous in living systems. Glutathione biosynthesis can be affected by biochemical individuality and\/or dietary factors. Chronic oxidative stress can also deplete cellular glutathione. Precursors to glutathione, such as whey protein, vitamin C, and glutamine, are often recommended to boost glutathione levels in the body; however, results are inconsistent. Biological individuality is such that not every body has equivalent ability to metabolize the precursor to raise glutathione.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWhy Not Give Pure Glutathione? \u003c\/span\u003e\u003cspan\u003eUnfortunately, most oral forms of glutathione are foul smelling, but more importantly, the majority of an oral dose is oxidized before it can be absorbed and used by the cells. This formulation delivers a unique preparation of glutathione that overcomes these usual limitations. The stability of S-acetylglutathione through the intestinal wall and the plasma is well documented in the literature. Oral intake of S-acetylglutathione increases total glutathione and percent-reduced glutathione. Percent-reduced glutathione is a very significant biomarker of health status.*\u003c\/span\u003e\u003cspan\u003e[1-5]\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMechanism of Absorption \u003c\/span\u003e\u003cspan\u003eS-acetylglutathione, a lipid-like compound, is taken up intact by chylomicrons in the gut. The acetyl bond is placed on its thiol group or sulfur group, which prevents oxidation and allows the molecule to pass diffusively into the cell after absorption in the gut. The bond is then cleaved by non-specific enzymes inside the cell. Acetylation prevents the breakdown of glutathione, and S-acetylglutathione does not require energy expenditure to be cleaved to reduced glutathione once it crosses the cell wall.*\u003c\/span\u003e\u003cspan\u003e[1-8]\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAntioxidant Activity \u003c\/span\u003e\u003cspan\u003eGlutathione functions extensively in tissues and organs throughout the body. It plays critical roles in protecting the body from oxidative stress, maintaining cellular functions, and supporting healthy immune function.\u003c\/span\u003e\u003cspan\u003e[1,4] \u003c\/span\u003e\u003cspan\u003eMany factors can increase cellular exposure to oxidative insult, and therefore increase cellular \u003cmeta charset=\"UTF-8\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003econsumption of nutrients—such as glutathione—that provide antioxidant activity. This may result in a fierce cycle of oxidative stress and challenges to detoxification. Complete biotransformation and protection from oxidative stress are important to maintaining cellular integrity and tissue health.*\u003c\/span\u003e\u003cspan\u003e[2,5]\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eOther Benefits of Maintaining Healthy Glutathione Levels \u003c\/span\u003e\u003cspan\u003eMuch information related to mitochondrial health has surfaced in the literature. Mitochondria, the energy-producing powerhouses of cells, are also the primary intracellular site of oxygen consumption and the major source of reactive oxygen species (ROS). S-acetylglutathione has been shown to cross the membrane of the mitochondria, increasing the organelle’s activity and minimizing ROS.\u003c\/span\u003e\u003cspan\u003e[8,9] \u003c\/span\u003e\u003cspan\u003eReduction of ROS is associated with maintaining mitochondrial integrity and function, and improved mitochondrial health is believed to support overall health and energy.*\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eS-acetylglutathione has also been shown to decrease TNF-alpha, NF- kappa beta, and F-2 isoprostane.\u003c\/span\u003e\u003cspan\u003e[4,9-12] \u003c\/span\u003e\u003cspan\u003eAdditionally, there is mounting evidence that intracellular glutathione levels in antigen-presenting cells (e.g. macrophages) may influence the Th1\/Th2 cytokine response pattern and promote a balanced immune reaction.*\u003c\/span\u003e\u003cspan\u003e[10]\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 2\" class=\"page\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eMedicinal Ingredients (per vegetarian capsule)\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eL-Glutathione (from S-Acetyl Glutathione) ........................................................ 100 mg \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eNon-Medicinal Ingredients\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eHypromellose (acid-resistant vegetarian capsule), microcrystalline cellulose, stearic acid, magnesium stearate, silica.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003eRecommended Dose\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eAdults: \u003c\/span\u003e\u003cspan\u003eTake one to two capsules one to two times daily or as directed by your healthcare practitioner.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eConsult your healthcare practitioner prior to use if you are pregnant or breastfeeding.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eStorage: \u003c\/span\u003e\u003cspan\u003eKeep tightly closed in a cool, dry place out of reach of children. Do not use if tamper seal is damaged.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDoes Not Contain: \u003c\/span\u003e\u003cspan\u003eWheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eNPN 80078405\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Xymogen","offers":[{"title":"Default Title","offer_id":39613283041383,"sku":"80078405","price":94.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0022\/7039\/6474\/products\/s-acetyl-glutathione-60c_can_071717.jpg?v=1643150268","url":"https:\/\/shop.rediscoverhealth.ca\/en-ru\/products\/s-acetyl-glutathione-60-caps","provider":"Rediscover Health Online Dispensary ","version":"1.0","type":"link"}