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Vitamin K2, D3 and A Helps Develop & Maintain Healthy Bones 30 ml

$21.60

Benefits

  • Offers balance of key fat-soluble vitamins, A, D, and K, critical to bone health
  • Contains vitamin K2 (MK-7), the most bioactive and long-lasting form
  • K2 (MK-7) helps increase vertebral bone mineral density among postmenopausal women
  • Provides vitamin D3 effective in maintaining blood levels of 25-OH vitamin D23
  • Optimal form of vitamin A, palmitate
  • Suitable for vegetarians

Feature Summary

Vitamin K2, D3 and A provides clinically relevant doses of the three fat-soluble vitamins essential to optimal bone health. Although needed for cardiovascular health, blood sugar regulation, immune function, and inflammation control, vitamins A, D, and K2 have complementary physiological bone-related functions, such as modulating gene expression in osteoblasts and carboxylating osteocalcin, an enzyme needed for bone formation.1 This is exemplified by a reduction in undercarboxylated osteocalcin and an increase in bone mineral density (BMD) in postmenopausal women when vitamin K is added to vitamin D supplementation.2,3,4

Vitamin D has diverse and significant functions in multiple body systems, and widespread deficiency magnifies these crucial roles.5,6 Supplementation is associated with a well-established reduction in osteoporotic fracture when taken daily at a clinically relevant dose.7,8 Correcting a vitamin D deficiency is critical when supplementing with vitamin A, as vitamin A appears to promote bone health if vitamin D levels are adequate.9,10,11 Additionally, maternal vitamin A levels during pregnancy have been associated with the peak bone mass and bone strength of their children, highlighting the unrecognized importance of vitamin A for lifelong bone health, in parallel to the effect of vitamin D on peak bone mass.12,13 Vitamin K is now recognized as necessary for the carboxylation of enzymes critical for both bone and blood vessel health.14-18 Indeed, meta-analysis has shown an improvement in vertebral bone mineral density (BMD) and a reduction in fracture among postmenopausal women with osteoporosis, while controlled trial data shows a reduction in the age-related decline in BMD among healthy postmenopausal women.19,20 The naturally derived MK-7 form in Vitamin K2, D3 and A has a longer half-life than any other form.21,22

Medicinal Ingredients

Serving Size: 0.25 ml
Servings Per Container: 120

Each Serving (0.25 ml) Contains:
Vitamin A (Palmitate).................................................... 500 IU (151 mcg RAE)
Vitamin D3 (Cholecalciferol) .......................................1000 IU (25 mcg)
Vitamin K2 (Menaquinone) (MK-7) (Natto Bean)......50 mcg

Non-Medicinal Ingredients

Medium chain triglycerides, organic flaxseed oil, natural vitamin E (non-GMO sunflower oil), natural vanilla flavour

Allergens:

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Benefits

  • Potent physiological balance of key fat-soluble vitamins, A, D, and K, critical to bone health
  • Contains vitamin K2 (MK-7), the most bioactive and long-lasting form
  • MK-7 shown to increases vertebral BMD among postmenopausal women
  • Provides vitamin D3, shown to be more effective than D2 in maintaining blood levels of 25-OH vitamin D17
  • Optimal form of vitamin A, palmitate, bypasses impaired conversion of carotenoids (affects nearly half the population)18
  • Helps develop and maintain healthy bones
  • Suitable for vegetarians

Feature Summary

Vitamin K2, D3 &A provides clinically relevant doses of the three fat-soluble vitamins essential to optimal bone health. Although needed for cardiovascular health, blood sugar regulation, immune function, and inflammation control, vitamins A, D, and K2 have complementary physiological bone-related functions, such as modulating gene expression in osteoblasts and carboxylating osteocalcin, an enzyme needed for bone formation.1 This is exemplified by a reduction in undercarboxylated osteocalcin and an increase in bone mineral density (BMD) in postmenopausal women when vitamin K is added to vitamin D supplementation.2

Vitamin D has diverse and significant functions in multiple body systems, and widespread deficiency magnifies these crucial roles.3,4 Supplementation is associated with a well-established reduction in osteoporotic fracture.5 Correcting a vitamin D deficiency is critical when supplementing with vitamin A, as vitamin A appears to promote bone health if vitamin D levels are adequate.6,7,8 Vitamin K is now recognized as being necessary not only for coagulation, but for the carboxylation of enzymes critical for both bone and blood vessel health.9-13 Indeed, meta-analysis has shown improvement in vertebral BMD and reduction in fracture among post-menopausal women with osteoporosis, while controlled trial data shows a reduction in the age-related decline in BMD among healthy postmenopausal women.14,15 The naturally derived MK-7 form in Vitamin K2, D3 &A has a longer half-life than any other form.16

Contraindications

Consult a health care practitioner prior to use if you are taking blood thinners. Keep out of reach of children.

Drug Interactions

Vitamin K may antagonize the effect of some anticoagulant medications, and concurrent use should be medically supervised. When taken with a thiazide medication (diuretic), vitamin D may increase the risk for hypercalcemia. Also, vitamin D may improve insulin sensitivity and lower blood pressure, requiring a reduction in dosage of hypertension and/or diabetic medications. Vitamin A should not be taken with other synthetic retinoids, such as acitretin or bexarotene.

NPN 80047935