Generically known as folate, 5-methyltetrahydrofolate (5-MTHF) is the most biologically active form of the water-soluble B vitamin, folic acid. It is the form into which the body must convert all other forms of folic acid before it can be used. Along with vitamin B12, 5-MTHF serves as a donor of methyl groups. The body utilizes methyl groups in many nervous system and metabolic processes, including the conversion of homocysteine to methionine, the synthesis of monoamine neurotransmitters (serotonin, dopamine, epinephrine), the production of melatonin, and the synthesis of DNA.
Folate intake is especially important for women of child-bearing age. Studies indicate that supplementing during pregnancy supports a healthy outcome.  In a 2010 study, researchers concluded that if a woman exhibits certain genetic variations during pregnancy, it will lead to reduced methylation capacity and subsequent DNA hypomethylation.*
Medicinal Ingredients (per vegetable capsule)
Folate ((6s)-5-Methyltetrahydrofolic acid, glucosamine salt, synthetic)........1000 mcg
Non-Medicinal Ingredient: Hypromellose, magnesium stearate, microcrystalline cellulose, silicon dioxide, stearic acid.
Adults: Take 1 capsule daily.